High-resolution respirometry
Hansatech Instruments respirometers are ideal choices for high-resolution, high sensitivity, cost-effective analysis of mitochondrial function, bioenergetics and other respirometry applications. Real-time oxygen flux measurements can be combined with simultaneous data from ion-selective electrodes (ISEs) to provide measurements of pH, calcium (Ca2+) or potassium (K+) activity, or membrane potential (TPP+).
Key features
Key features of the Hansatech instruments respirometry systems include:
- High-resolution for detection of small changes in oxygen consumption.
- Sealed sample chamber for liquid samples between 0.2 – 2.5ml.
- Integral or external sample temperature control.
- High-sensitivity Clark-type dissolved oxygen electrode.
- Real-time display of oxygen flux data.
- Simultaneous logging of pH data from a third-party pH electrode allowing analysis of extracellular acidification rates (ECAR) in addition to oxygen consumption rates (OCR).
- Analysis of oxygen flux alongside Ca2+, K+, TPP+ activity using ion-selective electrodes (ISEs).
- Easy additions of substrates/inhibitors/uncouplers to the sample.
- Data from up to 8 individual systems acquired simultaneously in real-time from a single Windows PC.
Common applications
Some of the different biomedical, biochemical and biotechnology research areas include:
- Mitochondrial dysfunction and disease.
- Neurology.
- Oncology/cancer research.
- Pharmaceuticals.
- Aging.
- Cardiology & cardiovascular disease research.
- Endocrinology including diabetes research.
- Hepatology.
- Bacterial and viral infectious diseases.
- Metabolomics.
- Kinesiology and exercise physiology research.
- Mycology.
- Ecotoxicology.
- Biophotovoltaics.
- Nano materials.
- Biorefining.
